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CancerGenomeLandscape Assay

The CancerGenomeLandscape assay is our state-of-the-art contribution to oncological precision medicine and the treatment of tumor diseases.

It refers to a comprehensive molecular genetic test that not only analyzes the activity of all of the tumor’s more than 20.000 genes (PANTHER-chip), but that simultaneously registers therapeutically relevant mutations in cancer and tumor suppressor genes.

Several of our MultiOncogen Mutation (MOM) tests are suitable mutation assays that complement the PANTHER-chip.

The right choice of MOM test depends both on the type of tumor and the precise treatment plan.

If, for instance, a cancer vaccination is also under consideration, it makes sense to choose exome sequencing as a concomitant MOM test since it offers a mutation analysis of the more than 20.000 tumor genes.

This is why the CancerGenomeLandscape assay carries its name: it offers a comprehensive image of the tumor’s entire molecular genetic landscape.

We also provide the patients and their oncologists with a molecular genetic report that contains all essential recommendations for an optimal treatment of the individual tumor disease with approved drugs and additionally, with those that are currently being tested in clinical trials and may be available under compassionate use.

Testing Requirements

Cryopreserved tumor tissue is ideal for the high resolution CancerGenomeLandscape chip technology. Fresh tumor cells from fresh pleural effusions or ascitic fluid are also suitable. Another option rests in formalin-fixed paraffin-embedded tissue. Minuscule tissue samples (for instances, a few of slices skin from a punch biopsy or tissue collected in fine-needle aspiration biopsies) suffice. Detailed information can be found in our Specimen Collection and Transport Kits.

Duration of Testing

Depending on the type of accompanying MOM test, 1 to 5 weeks.

Logistics

In all of Germany, the lead time for transporting cryopreserved tissue or tissue from pleural effusions and ascitic fluid is 24 hours before a planned procedure. We will contact the respective pathological institute to arrange for the FFPE tissue blocks. A single call will do, just ring us at 0211 4477 4388 (landline) or 0171 784 989 4 (cell). We will take care of the entire logistic process for you.

We are happy to consult you in finding the right treatment!